Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05828.1Manually curated; KEGG: hut:Huta_2000 6-pyruvoyltetrahydropterin synthase. (152 aa)    
Predicted Functional Partners:
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.988
AEN05829.1
PFAM: Alcohol dehydrogenase, zinc-binding; KEGG: hut:Huta_1999 alcohol dehydrogenase zinc-binding domain protein.
 
     0.970
AEN05827.1
PFAM: Methyltransferase type 11; KEGG: hut:Huta_2001 hypothetical protein.
 
     0.969
AEN05355.1
Queuosine biosynthesis protein QueD; KEGG: htu:Htur_1391 6-pyruvoyl-tetrahydropterin synthase-like protein; TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase-related.
     
 0.947
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.902
AEN05830.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hsl:OE2491F hypothetical protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.842
AEN05826.1
PFAM: Protein of unknown function DUF457, transmembrane; KEGG: hsl:OE2499F hypothetical protein.
       0.777
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
    
 0.631
AEN05831.1
PFAM: Aldo/keto reductase; Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: hla:Hlac_0519 aldo/keto reductase.
 
     0.621
AEN05825.1
KEGG: nph:NP3792A ferredoxin I 5.
       0.562
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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