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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
AEN05845.1KEGG: hje:HacjB3_10520 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. (330 aa)    
Predicted Functional Partners:
AEN05158.1
KEGG: nph:NP2192A 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit region; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel.
 
 
 0.998
AEN05159.1
KEGG: nph:NP2194A isopropylmalate isomerase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit region; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha.
 
 0.998
AEN05162.1
KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.
  
 0.996
AEN05163.1
TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: hma:rrnAC0330 acetolactate synthase large subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region.
 
 0.976
AEN04961.1
KEGG: hvo:HVO_A0489 homocitrate synthase; PFAM: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.971
AEN05023.1
Acetolactate synthase; KEGG: nmg:Nmag_2521 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Belongs to the TPP enzyme family.
 
 0.964
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
  
 0.961
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.959
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.954
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.947
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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