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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
AEN05849.1PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: hvo:HVO_2612 sugar kinase; Belongs to the carbohydrate kinase PfkB family. (294 aa)    
Predicted Functional Partners:
AEN05848.1
TIGRFAM: Putative translation initiation factor, aIF-2BII; Initiation factor 2B alpha/beta/delta; KEGG: hla:Hlac_2269 translation initiation factor IF-2B subunit delta; PFAM: Initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family.
  
 
 0.988
AEN06486.1
KEGG: hbo:Hbor_02570 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; Belongs to the phosphohexose mutase family.
 
 
 0.926
AEN06000.1
KEGG: hbo:Hbor_18320 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, C-terminal; Belongs to the phosphohexose mutase family.
 
 
 0.923
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: hla:Hlac_2699 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
    0.829
AEN05365.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.601
AEN05930.1
KEGG: hvo:HVO_2614 uridine phosphorylase; PFAM: Nucleoside phosphorylase.
   
 
 0.600
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.445
AEN05846.1
Cobalamin-independent synthase MetE domain protein; PFAM: Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal; KEGG: hvo:HVO_2743 methionine synthase vitamin-B12 independent.
       0.422
metE
Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
       0.422
AEN07300.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: hbo:Hbor_26610 2-keto-3-deoxygluconate kinase.
  
     0.413
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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