Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmcAProtein of unknown function DUF699 ATPase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (788 aa)    
Predicted Functional Partners:
AEN06151.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding region; KEGG: hvo:HVO_1670 nucleolar protein-like protein.
  
 0.991
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.987
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 0.977
AEN06513.1
KH domain protein; KEGG: hbo:Hbor_00890 universal archaeal kh domain protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology.
   
 0.977
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.958
AEN06411.1
KEGG: hvo:HVO_1965 Nob1p-like protein.
   
 
 0.935
rps28e
KEGG: hvo:HVO_2738 30S ribosomal protein S28.eR; HAMAP: 30S ribosomal protein S28e; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
   
   0.931
rps4e
KEGG: hvo:HVO_2552 30S ribosomal protein S4.eR; HAMAP: 30S ribosomal protein S4e; PFAM: Ribosomal protein S4e, central; Ribosomal protein S4e, N-terminal; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.922
rps3ae
KEGG: hla:Hlac_0618 30S ribosomal protein S3Ae; HAMAP: 30S ribosomal protein S3Ae; PFAM: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
  0.919
AEN06543.1
RIO-like kinase; KEGG: hla:Hlac_0533 protein of unknown function RIO1; PFAM: RIO-like kinase; RIO2 kinase, winged helix, N-terminal; SMART: RIO kinase.
  
 0.919
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.