Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05877.1KEGG: azc:AZC_3799 hypothetical protein. (179 aa)    
Predicted Functional Partners:
AEN05878.1
Hypothetical protein.
       0.773
AEN05876.1
CoA-disulfide reductase; KEGG: hbo:Hbor_04320 NAD(fad)-dependent dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
       0.651
AEN05879.1
Hypothetical protein.
       0.601
AEN05880.1
KEGG: hvo:HVO_1318 aminoglycoside N3-acetyltransferase; PFAM: Aminoglycoside 3-N-acetyltransferase.
       0.413
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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