STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN05881.1PFAM: CRISPR-associated protein Cas4; KEGG: hvo:HVO_2767 ATP-dependent DNA helicase Dna2. (925 aa)    
Predicted Functional Partners:
AEN05880.1
KEGG: hvo:HVO_1318 aminoglycoside N3-acetyltransferase; PFAM: Aminoglycoside 3-N-acetyltransferase.
       0.620
AEN04677.1
PFAM: Ribonuclease II/R; KEGG: hla:Hlac_0359 ribonuclease II.
  
 
 
 0.526
AEN05879.1
Hypothetical protein.
       0.472
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
 
 0.443
AEN05056.1
KEGG: nph:NP1508A family B DNA-directed DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; Hedgehog/intein hint, N-terminal.
  
   0.434
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
  
 
 
 0.430
AEN05287.1
PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; KEGG: hla:Hlac_1819 RNA polymerase insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type.
  
 
 
 0.427
AEN07262.1
PFAM: DNA helicase, UvrD/REP type; KEGG: hla:Hlac_0203 UvrD/REP helicase.
 
   0.417
AEN05876.1
CoA-disulfide reductase; KEGG: hbo:Hbor_04320 NAD(fad)-dependent dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 
     0.414
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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