Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glmS-2Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (618 aa)    
Predicted Functional Partners:
AEN06800.1
TIGRFAM: Glutamine synthetase type I; KEGG: hbo:Hbor_29510 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
 
 
 0.941
carB
TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: htu:Htur_3296 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; Belongs to the CarB family.
   
 0.933
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
0.926
purQ
Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
 0.924
pgi
KEGG: hbo:Hbor_05630 glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.922
carA
TIGRFAM: Carbamoyl phosphate synthase, small subunit; KEGG: hla:Hlac_2325 carbamoyl phosphate synthase small subunit; PFAM: Glutamine amidotransferase class-I, C-terminal; Carbamoyl phosphate synthase, small subunit, N-terminal; Belongs to the CarA family.
    
 0.918
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
  
 
0.901
AEN05882.1
Glucosamine-1-phosphate N-acetyltransferase; KEGG: hla:Hlac_1080 nucleotidyl transferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat.
 
   
 0.852
AEN05884.1
Protein of unknown function UPF0175; PFAM: Uncharacterised protein family UPF0175; KEGG: nmg:Nmag_0158 protein of unknown function UPF0175.
       0.556
AEN05885.1
KEGG: hma:rrnB0081 hypothetical protein.
       0.556
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (12%) [HD]