Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN05920.1KEGG: hla:Hlac_2592 CTP/GMP synthase operon protein. (108 aa)    
Predicted Functional Partners:
guaAB
GMP synthase (glutamine-hydrolyzing) subunit B; Catalyzes the synthesis of GMP from XMP.
       0.907
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.907
AEN05923.1
KEGG: hwa:HQ3198A menaquinol--cytochrome-c reductase.
       0.497
AEN05924.1
KEGG: hla:Hlac_2309 hypothetical protein.
       0.497
AEN05918.1
PFAM: Cupin 2, conserved barrel; KEGG: htu:Htur_2127 cupin 2 conserved barrel domain protein.
       0.445
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.