Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN05954.1KEGG: hbo:Hbor_02300 malate dehydrogenase (NAD); PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily. (304 aa)    
Predicted Functional Partners:
AEN06906.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: hla:Hlac_0723 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase-like.
  
 0.999
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.989
AEN04492.1
PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; KEGG: hbo:Hbor_08740 allosteric nADP-dependent malic enzyme.
  
 0.970
AEN05617.1
KEGG: hma:rrnAC2158 aconitate hydratase; TIGRFAM: Aconitase, putative; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel.
  
 0.969
AEN04531.1
KEGG: hbo:Hbor_21520 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II.
  
 0.930
AEN04749.1
Aspartate transaminase; KEGG: htu:Htur_1170 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.
  
 0.930
AEN05304.1
KEGG: hbo:Hbor_16150 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II.
  
 0.930
AEN06503.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: hsl:OE3634F isocitrate dehydrogenase (NADP); PFAM: Isocitrate/isopropylmalate dehydrogenase.
  
 0.928
AEN07018.1
KEGG: hvo:HVO_2588 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
  
 0.928
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; KEGG: htu:Htur_0284 glyceraldehyde-3-phosphate dehydrogenase, type II.
 
 
 0.915
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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