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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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Score
AEN05964.1Thioredoxin domain-containing protein; PFAM: Thioredoxin domain; KEGG: hvo:HVO_2786 thioredoxin. (107 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 0.779
AEN05667.1
KEGG: nph:NP3056A peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type.
   
 0.746
AEN05965.1
Histidine kinase; KEGG: hut:Huta_1571 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region.
   
 
 0.725
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.700
AEN06012.1
Heat shock protein DnaJ domain protein; KEGG: hbo:Hbor_22210 DnaJ-class molecular chaperone with C-terminal zn finger domain; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal.
   
 0.621
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.621
AEN04786.1
Dihydrolipoyl dehydrogenase; KEGG: hbo:Hbor_26630 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.536
AEN04817.1
Dihydrolipoyl dehydrogenase; KEGG: hbo:Hbor_32240 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
  
 0.536
AEN04819.1
TIGRFAM: Mercuric reductase MerA; KEGG: hla:Hlac_2994 mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.536
AEN04821.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hla:Hlac_2992 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
  
 0.536
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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