Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06040.1PcrB family protein; PFAM: Geranylgeranylglyceryl phosphate synthase-like; KEGG: hut:Huta_2960 PcrB family protein. (418 aa)    
Predicted Functional Partners:
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
     
 0.937
AEN06839.1
Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
  
  
 
0.921
AEN04516.1
KEGG: hla:Hlac_1294 galactoside O-acetyltransferase 3; maltose O-acetyltransferase 3.
 
   
 0.727
AEN05156.1
PFAM: Protein of unknown function DUF1405; KEGG: hbo:Hbor_07430 membrane protein.
  
     0.643
AEN06041.1
Hypothetical protein.
       0.628
AEN05512.1
PFAM: Bacterial extracellular solute-binding, family 1; KEGG: hma:rrnAC3197 trehalose/maltose binding protein.
  
     0.609
AEN06039.1
KEGG: hma:rrnAC0725 hypothetical protein.
       0.555
AEN06629.1
PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; GCN5-related N-acetyltransferase; KEGG: hbo:Hbor_00550 peroxiredoxin.
 
     0.549
AEN05606.1
Hypothetical protein; KEGG: tsc:TSC_c15780 N-6 DNA methylase family.
  
     0.537
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
       0.524
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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