Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06045.1Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: hvo:HVO_1666 phosphopantetheine adenylyltransferase; PFAM: Cytidylyltransferase. (171 aa)    
Predicted Functional Partners:
AEN06368.1
UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
  
 0.955
AEN06051.1
TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: hma:rrnAC3539 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein.
    
 0.908
AEN06046.1
KEGG: hla:Hlac_0951 transcriptional regulator, TrmB.
       0.880
AEN06879.1
Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
      0.799
AEN06813.1
PFAM: Auxin efflux carrier; KEGG: hbo:Hbor_25260 permease.
  
  
 0.567
gshA
Carboxylate-amine ligase ybdK; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
       0.543
AEN04492.1
PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; KEGG: hbo:Hbor_08740 allosteric nADP-dependent malic enzyme.
  
    0.529
AEN06151.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding region; KEGG: hvo:HVO_1670 nucleolar protein-like protein.
 
     0.518
AEN06411.1
KEGG: hvo:HVO_1965 Nob1p-like protein.
 
     0.511
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
     0.501
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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