Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06102.1PFAM: Blue (type 1) copper domain; KEGG: hma:pNG6063 halocyanin precursor-like. (179 aa)    
Predicted Functional Partners:
AEN06103.1
KEGG: htu:Htur_4294 bilirubin oxidase; PFAM: Multicopper oxidase, type 2; Multicopper oxidase, type 3.
 
 
 
 0.761
AEN05941.1
UspA domain-containing protein; PFAM: UspA; KEGG: hbo:Hbor_03850 universal stress family protein.
  
     0.474
AEN06374.1
PFAM: NHL repeat; KEGG: hvo:HVO_0336 hypothetical protein.
  
     0.467
AEN05480.1
KEGG: hla:Hlac_1531 protein of unknown function DUF75.
 
    0.456
AEN06696.1
KEGG: hwa:HQ3226A hypothetical protein.
  
     0.445
AEN06100.1
Hypothetical protein; Manually curated; KEGG: hsl:OE6265R hypothetical protein.
       0.444
tfb-2
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
       0.444
AEN05694.1
KEGG: hma:pNG6077 hypothetical protein.
  
     0.438
AEN07285.1
PFAM: GCN5-related N-acetyltransferase; KEGG: hbo:Hbor_08560 acetyltransferase.
  
     0.416
AEN06301.1
PFAM: Metallophosphoesterase; KEGG: hmu:Hmuk_0118 metallophosphoesterase.
 
   
 0.414
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (14%) [HD]