Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06158.1KEGG: hmu:Hmuk_2306 methionine adenosyltransferase; PFAM: S-adenosylmethionine synthetase (MAT), archaea. (260 aa)    
Predicted Functional Partners:
mat
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
  
  
 
0.906
AEN05241.1
Cysteine synthase; KEGG: hbo:Hbor_02440 oah/oas sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme.
     
  0.900
AEN05846.1
Cobalamin-independent synthase MetE domain protein; PFAM: Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal; KEGG: hvo:HVO_2743 methionine synthase vitamin-B12 independent.
     
  0.900
metE
Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
     
  0.900
AEN06159.1
Uncharacterized peroxidase-related enzyme; KEGG: hbo:Hbor_20090 alkylhydroperoxidase AhpD family core domain; TIGRFAM: Uncharacterised peroxidase-related; Alkylhydroperoxidase AhpD core; PFAM: Carboxymuconolactone decarboxylase.
       0.773
AEN06160.1
PFAM: Mechanosensitive ion channel MscS; KEGG: hbo:Hbor_20120 small-conductance mechanosensitive channel.
       0.549
AEN07255.1
KEGG: hla:Hlac_1971 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
 
     0.486
AEN06157.1
PFAM: Ornithine cyclodeaminase/mu-crystallin; KEGG: hvo:HVO_2950 ornithine cyclodeaminase.
       0.461
AEN07134.1
PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: hla:Hlac_0806 peptidylprolyl isomerase FKBP-type.
 
  
 0.449
carS
UPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
 
     0.446
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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