Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06182.1PFAM: GHMP kinase; KEGG: hbo:Hbor_04760 kinase, sugar kinase superfamily. (259 aa)    
Predicted Functional Partners:
htpX
Protease htpX; KEGG: hwa:HQ3431A heat shock protein HtpX; HAMAP: protease htpX; PFAM: Peptidase M48, Ste24p; Belongs to the peptidase M48B family.
  
    0.786
AEN05324.1
PFAM: Peptidase M48, Ste24p; KEGG: hmu:Hmuk_0373 peptidase M48 Ste24p.
  
    0.786
metE
Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
  
    0.783
aroK
PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: hut:Huta_3025 shikimate kinase.
 
     0.703
AEN05775.1
PFAM: Threonyl/alanyl tRNA synthetase, SAD; Alanyl-tRNA synthetase, class IIc, N-terminal; Phosphoesterase, DHHA1; KEGG: hvo:HVO_2717 alanyl-tRNA synthetase.
  
    0.624
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.624
AEN06184.1
Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II.
       0.620
rpoL
DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
 
     0.615
AEN04492.1
PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; KEGG: hbo:Hbor_08740 allosteric nADP-dependent malic enzyme.
  
    0.566
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
 
     0.554
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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