| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN06177.1 | AEN06184.1 | Halar_2523 | Halar_2530 | KEGG: hbo:Hbor_19060 hypothetical protein. | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | 0.687 |
| AEN06177.1 | aroK | Halar_2523 | Halar_2529 | KEGG: hbo:Hbor_19060 hypothetical protein. | PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: hut:Huta_3025 shikimate kinase. | 0.730 |
| AEN06182.1 | AEN06184.1 | Halar_2528 | Halar_2530 | PFAM: GHMP kinase; KEGG: hbo:Hbor_04760 kinase, sugar kinase superfamily. | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | 0.620 |
| AEN06182.1 | aroK | Halar_2528 | Halar_2529 | PFAM: GHMP kinase; KEGG: hbo:Hbor_04760 kinase, sugar kinase superfamily. | PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: hut:Huta_3025 shikimate kinase. | 0.703 |
| AEN06184.1 | AEN06177.1 | Halar_2530 | Halar_2523 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | KEGG: hbo:Hbor_19060 hypothetical protein. | 0.687 |
| AEN06184.1 | AEN06182.1 | Halar_2530 | Halar_2528 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | PFAM: GHMP kinase; KEGG: hbo:Hbor_04760 kinase, sugar kinase superfamily. | 0.620 |
| AEN06184.1 | AEN06902.1 | Halar_2530 | Halar_3292 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | KEGG: hvo:HVO_0008 aspartokinase; TIGRFAM: Aspartate kinase region; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | 0.664 |
| AEN06184.1 | aroA-2 | Halar_2530 | Halar_3521 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.910 |
| AEN06184.1 | aroB | Halar_2530 | Halar_0977 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.799 |
| AEN06184.1 | aroC | Halar_2530 | Halar_3523 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.979 |
| AEN06184.1 | aroE | Halar_2530 | Halar_1319 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.561 |
| AEN06184.1 | aroK | Halar_2530 | Halar_2529 | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: hut:Huta_3025 shikimate kinase. | 0.917 |
| AEN06902.1 | AEN06184.1 | Halar_3292 | Halar_2530 | KEGG: hvo:HVO_0008 aspartokinase; TIGRFAM: Aspartate kinase region; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. | 0.664 |
| AEN06902.1 | aroA-2 | Halar_3292 | Halar_3521 | KEGG: hvo:HVO_0008 aspartokinase; TIGRFAM: Aspartate kinase region; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.603 |
| AEN06902.1 | aroC | Halar_3292 | Halar_3523 | KEGG: hvo:HVO_0008 aspartokinase; TIGRFAM: Aspartate kinase region; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.632 |
| AEN06902.1 | aroE | Halar_3292 | Halar_1319 | KEGG: hvo:HVO_0008 aspartokinase; TIGRFAM: Aspartate kinase region; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.543 |
| AEN06902.1 | aroK | Halar_3292 | Halar_2529 | KEGG: hvo:HVO_0008 aspartokinase; TIGRFAM: Aspartate kinase region; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. | PFAM: GHMP kinase; GHMP kinase, C-terminal; TIGRFAM: Shikimate kinase, archaea; HAMAP: Shikimate kinase; KEGG: hut:Huta_3025 shikimate kinase. | 0.833 |
| aroA | aroB | Halar_3168 | Halar_0977 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.994 |
| aroA | aroC | Halar_3168 | Halar_3523 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.402 |
| aroA | aroE | Halar_3168 | Halar_1319 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.426 |