STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN06184.1Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II. (96 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.986
AEN04505.1
PFAM: Prephenate dehydrogenase; KEGG: hla:Hlac_1779 prephenate dehydrogenase.
 
 
 0.969
AEN06775.1
KEGG: hla:Hlac_0264 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT.
  
 
 0.949
AEN05062.1
TIGRFAM: Glutamine amidotransferase of anthranilate synthase; KEGG: hbo:Hbor_25070 aminodeoxychorismate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I, C-terminal.
  
 
 0.931
AEN05063.1
TIGRFAM: Para-aminobenzoate synthase/anthranilate synthase, component I; KEGG: htu:Htur_1366 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal.
  
 
 0.931
AEN05810.1
TIGRFAM: Glutamine amidotransferase of anthranilate synthase; KEGG: hmu:Hmuk_1768 glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I, C-terminal.
  
 
 0.931
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
  
 
 0.931
aroA-2
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.930
AEN05233.1
TIGRFAM: Isochorismate synthase; KEGG: hje:HacjB3_08360 isochorismate synthase; PFAM: Chorismate binding, C-terminal.
  
 
 0.919
rpl29
KEGG: hvo:HVO_2557 50S ribosomal protein L29; TIGRFAM: Ribosomal protein L29; PFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
  
    0.889
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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