Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06215.1PFAM: Methyltransferase type 11; KEGG: hbo:Hbor_17580 methyltransferase. (207 aa)    
Predicted Functional Partners:
AEN06216.1
KEGG: htu:Htur_1799 hypothetical protein.
       0.907
pus10
Conserved hypothetical protein CHP01213; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
     0.673
tfb-3
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
 
     0.599
AEN04507.1
Universal diphthamide biosynthesis domain-containing protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
 
     0.578
AEN06596.1
PFAM: Putative RNA methylase; KEGG: htu:Htur_0132 putative RNA methylase.
  
 
 0.572
AEN05545.1
Methylase; KEGG: hbo:Hbor_12120 HemK-related methylase; TIGRFAM: Putative methylase; PFAM: Methyltransferase small.
 
   
 0.564
AEN06395.1
PFAM: Cation/H+ exchanger; KEGG: hje:HacjB3_06465 sodium/hydrogen exchanger.
  
    0.551
AEN06059.1
Phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown.
 
     0.506
rpoL
DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
  
    0.476
rpl10e
TIGRFAM: Ribosomal protein L10e; HAMAP: 50S ribosomal protein L10e; KEGG: hla:Hlac_0057 50S ribosomal protein L10e; PFAM: Ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family.
 
    0.436
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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