STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN06226.1Shwachman-Bodian-Diamond syndrome protein; KEGG: hbo:Hbor_18900 hypothetical protein; TIGRFAM: Ribosome maturation protein SBDS; PFAM: Ribosome maturation protein SBDS, N-terminal; Ribosome maturation protein SBDS, C-terminal. (241 aa)    
Predicted Functional Partners:
rpl37ae
Ribosomal L37ae protein; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family.
 
   0.963
rpl10
Acidic ribosomal protein P0-like protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.929
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
 
 0.922
rpl30
KEGG: nph:NP4896A 50S ribosomal protein L30P; TIGRFAM: Ribosomal protein L30, archaeal; PFAM: Ribosomal protein L30p/L7e, conserved region.
  
 0.886
rps8e
TIGRFAM: Ribosomal protein S8e; HAMAP: 30S ribosomal protein S8e; KEGG: hbo:Hbor_08040 SSU ribosomal protein s8e; PFAM: Ribosomal protein S8e.
  
 0.884
rps19e
Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.884
eif6
Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
 
 
 0.874
rpl15e
KEGG: hwa:HQ1424A 50S ribosomal protein L15e; HAMAP: 50S ribosomal protein L15e; PFAM: Ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
   0.865
rps28e
KEGG: hvo:HVO_2738 30S ribosomal protein S28.eR; HAMAP: 30S ribosomal protein S28e; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
   0.859
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
   0.858
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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