Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06240.1SMART: Water Stress/Hypersensitive response domain; KEGG: hvo:HVO_1184 membrane protein NosY precursor. (376 aa)    
Predicted Functional Partners:
AEN06239.1
PFAM: Major facilitator superfamily MFS-1; KEGG: hvo:HVO_1349 sugar transporter.
       0.537
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.424
AEN06337.1
KEGG: hbo:Hbor_04610 hypothetical protein.
       0.424
AEN05247.1
KEGG: nmg:Nmag_1239 hypothetical protein.
       0.423
AEN06238.1
Regulatory protein ArsR; KEGG: hbo:Hbor_18830 transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.
       0.401
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (14%) [HD]