Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06246.1Histone acetyltransferase, ELP3 family; SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Histone acetyltransferase ELP3; KEGG: hla:Hlac_1480 histone acetyltransferase, ELP3 family; PFAM: Radical SAM; GCN5-related N-acetyltransferase. (553 aa)    
Predicted Functional Partners:
AEN04593.1
PFAM: Protein of unknown function Met10; KEGG: hvo:HVO_0929 putative methyltransferase.
 
  
 0.784
AEN06530.1
Protein of unknown function UPF0021; KEGG: hvo:HVO_0580 N-type ATP pyrophosphatase superfamily protein; TIGRFAM: Uncharacterised protein family UPF0021, C-terminal; PFAM: PP-loop.
  
 
 0.778
AEN04779.1
NMD3 family protein; PFAM: NMD3; KEGG: hbo:Hbor_01210 nmd protein affecting ribosome stability and mRNA decay.
   
    0.769
tuf
Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 
   0.741
AEN05274.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; Ribosomal protein S1, RNA binding domain; KEGG: hla:Hlac_1616 nucleic acid binding OB-fold tRNA/helicase-type.
       0.730
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
   
  
 0.669
AEN04606.1
KEGG: hla:Hlac_0782 small GTP-binding protein; TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; TGS.
  
    0.653
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
  
  
 0.638
prf1
Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
  
    0.617
AEN06391.1
Small GTP-binding protein; KEGG: hbo:Hbor_05240 GTPase; TIGRFAM: Small GTP-binding protein; PFAM: Nucleolar GTP-binding 1.
  
    0.604
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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