Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06253.1KEGG: hwa:HQ2415A hypothetical protein. (133 aa)    
Predicted Functional Partners:
AEN06254.1
PFAM: Methyltransferase type 11; KEGG: hbo:Hbor_13870 methylase involved in ubiquinone/menaquinone biosynthesis.
       0.795
AEN06255.1
PFAM: GCN5-related N-acetyltransferase; KEGG: hbo:Hbor_13860 hypothetical protein.
       0.658
AEN06252.1
PFAM: Major facilitator superfamily MFS-1; KEGG: hwa:HQ1487A oxalate/formate antiporter.
       0.584
AEN06251.1
KEGG: hbo:Hbor_13910 ornithine cyclodeaminase; PFAM: Ornithine cyclodeaminase/mu-crystallin.
       0.424
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
       0.406
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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