Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06282.1PFAM: GCN5-related N-acetyltransferase; KEGG: hje:HacjB3_16631 protein N-acetyltransferase-like protein. (151 aa)    
Predicted Functional Partners:
AEN06281.1
Acetate--CoA ligase; KEGG: hla:Hlac_0990 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase.
  
  
 0.556
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.553
AEN06284.1
SMART: DNA topoisomerase, type IIA, subunit B or N-terminal; ATP-binding region, ATPase-like; Hedgehog/intein hint, N-terminal; Hedgehog/intein hint domain, C-terminal; TIGRFAM: DNA gyrase, subunit B; Intein splicing site; KEGG: syn:sll2005 DNA gyrase B subunit; PFAM: DNA topoisomerase, type IIA, subunit B, region 2; ATP-binding region, ATPase-like; Toprim domain; DNA topoisomerase, type IIA, subunit B, C-terminal.
       0.487
AEN07174.1
YYY membrane protein; KEGG: hvo:HVO_0702 hypothetical protein; TIGRFAM: YYY membrane protein; PFAM: YYY membrane protein.
  
    0.446
AEN06198.1
N-acetylneuraminate synthase; KEGG: bja:blr5971 polysaccharide biosynthesis related protein; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; Xylose isomerase, TIM barrel domain.
  
  
 0.430
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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