STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN06282.1PFAM: GCN5-related N-acetyltransferase; KEGG: hje:HacjB3_16631 protein N-acetyltransferase-like protein. (151 aa)    
Predicted Functional Partners:
AEN06198.1
N-acetylneuraminate synthase; KEGG: bja:blr5971 polysaccharide biosynthesis related protein; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; Xylose isomerase, TIM barrel domain.
  
  
 0.573
AEN06281.1
Acetate--CoA ligase; KEGG: hla:Hlac_0990 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase.
  
  
 0.568
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.543
AEN06284.1
SMART: DNA topoisomerase, type IIA, subunit B or N-terminal; ATP-binding region, ATPase-like; Hedgehog/intein hint, N-terminal; Hedgehog/intein hint domain, C-terminal; TIGRFAM: DNA gyrase, subunit B; Intein splicing site; KEGG: syn:sll2005 DNA gyrase B subunit; PFAM: DNA topoisomerase, type IIA, subunit B, region 2; ATP-binding region, ATPase-like; Toprim domain; DNA topoisomerase, type IIA, subunit B, C-terminal.
       0.491
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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