Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06371.1KEGG: hvo:HVO_1900 putative RNA-binding protein. (128 aa)    
Predicted Functional Partners:
AEN06513.1
KH domain protein; KEGG: hbo:Hbor_00890 universal archaeal kh domain protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology.
  
 0.982
AEN06370.1
TIGRFAM: DNA-directed RNA polymerase; KEGG: hla:Hlac_2396 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain.
 
  
 0.939
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
 
     0.937
AEN06368.1
UPF0218 protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.926
eif2g
Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
    0.914
AEN06151.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding region; KEGG: hvo:HVO_1670 nucleolar protein-like protein.
   
 
 0.885
AEN06365.1
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
       0.846
rps24e
KEGG: hbo:Hbor_05010 SSU ribosomal protein s24e; HAMAP: 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    0.804
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
 0.754
AEN04588.1
KEGG: hbo:Hbor_22960 snornp protein gar1.
   
 
 0.751
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (12%) [HD]