Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (511 aa)    
Predicted Functional Partners:
AEN05186.1
Glycerol-3-phosphate dehydrogenase; KEGG: hmu:Hmuk_2572 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 
 0.973
AEN04510.1
PFAM: Peptidase S1/S6, chymotrypsin/Hap; KEGG: hma:rrnAC0296 serine protease HtrA.
   
 0.946
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 0.913
AEN06328.1
SMART: ATPase, AAA+ type, core; TIGRFAM: 26S proteasome subunit P45; KEGG: hbo:Hbor_05530 proteasome-activating nucleotidase; PFAM: ATPase, AAA-type, core; Belongs to the AAA ATPase family.
  
 0.913
AEN04927.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: hbo:Hbor_21950 proteasome rpn11 subunit jamm motif protein.
   
 0.906
AEN05625.1
KEGG: hla:Hlac_1268 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1.
   
 0.906
rpl40e
KEGG: hut:Huta_1320 50S ribosomal protein L40e; HAMAP: 50S ribosomal protein L40e; PFAM: Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
    
 0.855
AEN07243.1
Acylaminoacyl-peptidase; KEGG: gct:GC56T3_2594 peptidase S9 prolyl oligopeptidase active site domain protein.
  
 0.795
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.716
psmA-2
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.716
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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