Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06405.1PFAM: Histidine triad (HIT) protein; KEGG: hvo:HVO_2601 histidine triad protein. (182 aa)    
Predicted Functional Partners:
map
Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
 
 
 0.775
AEN06404.1
KEGG: hmu:Hmuk_1513 cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein.
       0.677
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  0.634
tbp-2
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  0.634
AEN06403.1
Beta-carotene 15,15'-monooxygenase; KEGG: srm:SRM_00147 retinal pigment epithelial membrane protein; PFAM: Carotenoid oxygenase.
       0.531
AEN06645.1
PFAM: Methyltransferase type 11; KEGG: hvo:HVO_0309 membrane protein.
 
   
 0.519
udk
TIGRFAM: Uridine kinase; HAMAP: Uridine kinase; KEGG: hla:Hlac_1557 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase.
   
 0.514
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
 0.503
AEN06800.1
TIGRFAM: Glutamine synthetase type I; KEGG: hbo:Hbor_29510 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
  
   0.498
AEN04719.1
TIGRFAM: Cysteine desulfurase, SufS; KEGG: hbo:Hbor_34450 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; NIF system FeS cluster assembly, NifU, N-terminal.
  
 
 0.491
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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