Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pgiKEGG: hbo:Hbor_05630 glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family. (428 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.997
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.995
AEN06733.1
TIGRFAM: Pyruvate kinase; KEGG: hma:rrnAC0546 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; Belongs to the pyruvate kinase family.
 
 0.987
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; KEGG: htu:Htur_0284 glyceraldehyde-3-phosphate dehydrogenase, type II.
  
 0.981
pgk
HAMAP: Phosphoglycerate kinase; KEGG: hla:Hlac_2372 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.956
AEN06734.1
ROK family protein; PFAM: ROK; KEGG: hla:Hlac_0043 ROK family protein.
 
 
 0.943
fbp
KEGG: hla:Hlac_2458 fructose-1,6-bisphosphatase; HAMAP: Fructose-1,6-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
  
 
 0.934
AEN06486.1
KEGG: hbo:Hbor_02570 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; Belongs to the phosphohexose mutase family.
  
 
 0.925
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.922
glmS-2
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.922
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (6%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.