Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06432.1TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; GAF; KEGG: hbo:Hbor_10850 fused histidine kinase with gaf domain/response regulator receiver; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; PAS. (615 aa)    
Predicted Functional Partners:
AEN06776.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver region; PAS fold-4; PAS fold; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; KEGG: hma:rrnAC0848 HTR-like protein; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like.
 
   
0.604
AEN05212.1
KEGG: hla:Hlac_1208 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; HalX; SMART: Signal transduction response regulator, receiver region.
 
   
 0.552
AEN06434.1
NADPH:quinone reductase; KEGG: hla:Hlac_1815 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like.
  
  
 0.453
AEN06826.1
KEGG: hmu:Hmuk_0317 hypothetical protein.
  
     0.448
AEN06433.1
KEGG: hbo:Hbor_09330 hypothetical protein.
       0.440
AEN06108.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Bacterio-opsin activator, HTH; PAS fold-4; Signal transduction response regulator, receiver region; GAF; KEGG: hje:HacjB3_18828 bacterio-opsin activator-like protein; SMART: PAS; Signal transduction response regulator, receiver region; GAF.
 
   
 0.400
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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