Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
msrAPeptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (177 aa)    
Predicted Functional Partners:
AEN06425.1
TIGRFAM: Methionine sulphoxide reductase B; KEGG: hvo:HVO_2234 methionine-R-sulfoxide reductase; PFAM: Methionine sulphoxide reductase B.
 
 0.989
AEN05206.1
PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: hla:Hlac_1351 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
   
 0.700
AEN05964.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin domain; KEGG: hvo:HVO_2786 thioredoxin.
   
 0.700
AEN06915.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin domain; KEGG: hbo:Hbor_27560 thioredoxin domain-containing protein.
   
 0.700
AEN07141.1
Thioredoxin; KEGG: hbo:Hbor_15610 thioredoxin.
   
 0.700
AEN06530.1
Protein of unknown function UPF0021; KEGG: hvo:HVO_0580 N-type ATP pyrophosphatase superfamily protein; TIGRFAM: Uncharacterised protein family UPF0021, C-terminal; PFAM: PP-loop.
    
 0.638
AEN06459.1
KEGG: hbo:Hbor_00940 hypothetical protein.
       0.519
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.514
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.493
AEN05771.1
Glutaredoxin; KEGG: hbo:Hbor_08290 glutaredoxin-like protein; manually curated; PFAM: Glutaredoxin.
  
 
 0.490
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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