Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06477.1HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: hbo:Hbor_03030 haloacid dehalogenase superfamily enzyme, subfamily IA; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase-like hydrolase. (217 aa)    
Predicted Functional Partners:
AEN06476.1
PFAM: DNA topoisomerase, type IA, zn finger; KEGG: hvo:HVO_2953 topoisomerase DNA binding C4 zinc finger.
       0.680
AEN05195.1
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
 
  
 0.619
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
       0.558
trpS
Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp).
       0.530
AEN06198.1
N-acetylneuraminate synthase; KEGG: bja:blr5971 polysaccharide biosynthesis related protein; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; Xylose isomerase, TIM barrel domain.
     
 0.468
pgk
HAMAP: Phosphoglycerate kinase; KEGG: hla:Hlac_2372 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 
 0.455
pgi
KEGG: hbo:Hbor_05630 glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.428
AEN07100.1
KEGG: htu:Htur_0531 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal.
 
  
 0.406
AEN05511.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: cyc:PCC7424_1896 binding-protein-dependent transport systems inner membrane component.
 
  
 0.403
AEN04965.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: hvo:HVO_A0493 ABC-type transport system permease protein (probable substrate sugar).
 
  
 0.402
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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