Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06479.1KEGG: nmg:Nmag_1670 MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; PFAM: Multi antimicrobial extrusion protein MatE. (480 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
     
 0.729
AEN06478.1
KEGG: hla:Hlac_2508 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Sec63 domain; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
   
   0.590
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; KEGG: htu:Htur_0284 glyceraldehyde-3-phosphate dehydrogenase, type II.
  
  
 0.496
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
  0.483
AEN05197.1
Squalene synthase; KEGG: hbo:Hbor_21020 farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase.
   
  
 0.471
AEN05803.1
Phytoene synthase; KEGG: hwa:HQ2860A geranylgeranyl-diphosphate geranylgeranyltransferase (phytoene synthase); PFAM: Squalene/phytoene synthase.
   
  
 0.471
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
    0.469
tbp-2
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
    0.469
AEN07243.1
Acylaminoacyl-peptidase; KEGG: gct:GC56T3_2594 peptidase S9 prolyl oligopeptidase active site domain protein.
   
  0.449
rnp2
Ribonuclease P protein component 2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
     
 0.432
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.