Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (316 aa)    
Predicted Functional Partners:
AEN06483.1
Dihydrolipoyllysine-residue acetyltransferase; KEGG: hla:Hlac_0141 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
 
 
 0.959
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 0.958
AEN05635.1
PFAM: Biotin/lipoate A/B protein ligase; KEGG: hvo:HVO_1815 biotin/lipoate A/B protein ligase family domain-containing protein.
  
 
 0.927
AEN06536.1
PFAM: Biotin/lipoate A/B protein ligase; KEGG: hvo:HVO_0572 lipoate protein ligase.
  
 
 0.927
AEN04660.1
Nitrogen-fixing NifU domain-containing protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; KEGG: hbo:Hbor_27860 thioredoxin-like protein.
  
 0.744
AEN04770.1
PFAM: NIF system FeS cluster assembly, NifU, C-terminal; KEGG: hla:Hlac_0148 nitrogen-fixing NifU domain protein.
  
 0.744
AEN06479.1
KEGG: nmg:Nmag_1670 MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; PFAM: Multi antimicrobial extrusion protein MatE.
     
 0.729
AEN05115.1
TIGRFAM: O-succinylbenzoate-CoA ligase; KEGG: hbo:Hbor_18630 O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase.
  
 
 0.713
AEN06481.1
TIGRFAM: Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x; KEGG: hla:Hlac_0139 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase, E1 component.
     
 0.710
AEN06482.1
Pyruvate dehydrogenase (acetyl-transferring); KEGG: hla:Hlac_0140 transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal.
  
  
 0.705
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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