Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN06497.1PFAM: Amino acid-binding ACT; KEGG: nph:NP1404A hypothetical protein. (166 aa)    
Predicted Functional Partners:
AEN06496.1
PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; KEGG: hvo:HVO_2983 hypothetical protein.
       0.907
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
       0.846
hisB
HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: hla:Hlac_2701 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase.
       0.730
AEN06498.1
KEGG: hvo:HVO_2985 hypothetical protein.
       0.693
AEN06694.1
Transcriptional regulator, XRE family; HAMAP: HTH-type transcriptional regulatory protein; PFAM: Helix-turn-helix type 3; KEGG: hbo:Hbor_28330 transcriptional regulator, xre family; SMART: Helix-turn-helix type 3.
  
     0.664
mptD
Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.638
AEN04927.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: hbo:Hbor_21950 proteasome rpn11 subunit jamm motif protein.
  
     0.629
AEN06168.1
Hypothetical protein; Manually curated; KEGG: hut:Huta_0046 hypothetical protein.
  
     0.628
AEN05448.1
UPF0179 protein; KEGG: hvo:HVO_2851 hypothetical protein; HAMAP: UPF0179 protein; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
  
   
 0.622
AEN06895.1
KEGG: hvo:HVO_0013 putative KEOPS complex component.
  
     0.614
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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