Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06500.1PFAM: Cupin 2, conserved barrel; KEGG: hje:HacjB3_06565 cupin 2 conserved barrel domain protein. (113 aa)    
Predicted Functional Partners:
AEN06501.1
KEGG: hsl:OE1067R hypothetical protein.
       0.701
AEN06502.1
KEGG: hma:pNG4024 hypothetical protein.
       0.630
hisB
HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: hla:Hlac_2701 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase.
       0.546
AEN06469.1
KEGG: hbo:Hbor_09950 hypothetical protein.
       0.456
rad25
Type III restriction protein res subunit; KEGG: hbo:Hbor_14720 DNA/RNA helicase, superfamily II; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
  
  
 0.414
AEN04558.1
KEGG: hvo:HVO_0721 hypothetical protein.
  
     0.408
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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