Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prf1Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (447 aa)    
Predicted Functional Partners:
AEN07268.1
KEGG: hvo:HVO_0424 ABC transporter ATP-binding protein; PFAM: RNase L inhibitor RLI, possible metal-binding region; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; ABC transporter-like; SMART: ATPase, AAA+ type, core.
  
 
 0.971
tuf
Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.967
rpl15e
KEGG: hwa:HQ1424A 50S ribosomal protein L15e; HAMAP: 50S ribosomal protein L15e; PFAM: Ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.944
pelA
Pelota-like protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
  
 
 0.921
rps15
PFAM: Ribosomal protein S15; Ribosomal protein S13/S15, N-terminal; KEGG: hbo:Hbor_20930 SSU ribosomal protein s15p.
 
 0.901
rpl10
Acidic ribosomal protein P0-like protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.888
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
  0.879
rpl19e
Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
  0.878
rps4e
KEGG: hvo:HVO_2552 30S ribosomal protein S4.eR; HAMAP: 30S ribosomal protein S4e; PFAM: Ribosomal protein S4e, central; Ribosomal protein S4e, N-terminal; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.877
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
  
  0.875
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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