| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN04586.1 | dnaG | Halar_0816 | Halar_2581 | KEGG: htu:Htur_0798 PUA domain containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.566 |
| AEN04586.1 | priS | Halar_0816 | Halar_1847 | KEGG: htu:Htur_0798 PUA domain containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.613 |
| AEN04586.1 | ribK | Halar_0816 | Halar_2887 | KEGG: htu:Htur_0798 PUA domain containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase. | Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.673 |
| AEN04586.1 | tiaS | Halar_0816 | Halar_3068 | KEGG: htu:Htur_0798 PUA domain containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.724 |
| AEN06418.1 | ribK | Halar_2783 | Halar_2887 | PFAM: NADPH-dependent FMN reductase; KEGG: hla:Hlac_1047 NADPH-dependent FMN reductase. | Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.900 |
| AEN06418.1 | ribL | Halar_2783 | Halar_1172 | PFAM: NADPH-dependent FMN reductase; KEGG: hla:Hlac_1047 NADPH-dependent FMN reductase. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.900 |
| AEN06519.1 | AEN07265.1 | Halar_2888 | Halar_3691 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.981 |
| AEN06519.1 | argS | Halar_2888 | Halar_2886 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: hut:Huta_2012 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.805 |
| AEN06519.1 | ilvE | Halar_2888 | Halar_2889 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.773 |
| AEN06519.1 | ribK | Halar_2888 | Halar_2887 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.907 |
| AEN06519.1 | ribL | Halar_2888 | Halar_1172 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.424 |
| AEN07265.1 | AEN06519.1 | Halar_3691 | Halar_2888 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.981 |
| AEN07265.1 | ribK | Halar_3691 | Halar_2887 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.900 |
| argS | AEN06519.1 | Halar_2886 | Halar_2888 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: hut:Huta_2012 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.805 |
| argS | dnaG | Halar_2886 | Halar_2581 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: hut:Huta_2012 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.565 |
| argS | ilvE | Halar_2886 | Halar_2889 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: hut:Huta_2012 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.491 |
| argS | ribK | Halar_2886 | Halar_2887 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: hut:Huta_2012 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.746 |
| dnaG | AEN04586.1 | Halar_2581 | Halar_0816 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | KEGG: htu:Htur_0798 PUA domain containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase. | 0.566 |
| dnaG | argS | Halar_2581 | Halar_2886 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: hut:Huta_2012 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.565 |
| dnaG | priS | Halar_2581 | Halar_1847 | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.989 |