| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN05162.1 | AEN06519.1 | Halar_1423 | Halar_2888 | KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.559 |
| AEN05162.1 | argC | Halar_1423 | Halar_1203 | KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.548 |
| AEN05162.1 | glyA | Halar_1423 | Halar_1721 | KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.456 |
| AEN05162.1 | ilvE | Halar_1423 | Halar_2889 | KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.696 |
| AEN05187.1 | AEN06519.1 | Halar_1451 | Halar_2888 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.923 |
| AEN05187.1 | AEN07265.1 | Halar_1451 | Halar_3691 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.979 |
| AEN05187.1 | ribH | Halar_1451 | Halar_0759 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.929 |
| AEN06519.1 | AEN05162.1 | Halar_2888 | Halar_1423 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | KEGG: hje:HacjB3_10545 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.559 |
| AEN06519.1 | AEN05187.1 | Halar_2888 | Halar_1451 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 0.923 |
| AEN06519.1 | AEN07265.1 | Halar_2888 | Halar_3691 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.981 |
| AEN06519.1 | argC | Halar_2888 | Halar_1203 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.549 |
| AEN06519.1 | argS | Halar_2888 | Halar_2886 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: hut:Huta_2012 arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.805 |
| AEN06519.1 | glyA | Halar_2888 | Halar_1721 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.510 |
| AEN06519.1 | ilvE | Halar_2888 | Halar_2889 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.773 |
| AEN06519.1 | ribH | Halar_2888 | Halar_0759 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
| AEN06519.1 | ribK | Halar_2888 | Halar_2887 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.907 |
| AEN06519.1 | rps2 | Halar_2888 | Halar_1548 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Ribosomal protein S2; KEGG: hbo:Hbor_12460 SSU ribosomal protein s2p; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.559 |
| AEN07265.1 | AEN05187.1 | Halar_3691 | Halar_1451 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 0.979 |
| AEN07265.1 | AEN06519.1 | Halar_3691 | Halar_2888 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.981 |
| AEN07265.1 | ribH | Halar_3691 | Halar_0759 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |