Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06577.1TIGRFAM: Peptidase S26B, eukaryotic signal peptidase; KEGG: hvo:HVO_0002 signal peptidase I. (303 aa)    
Predicted Functional Partners:
AEN04510.1
PFAM: Peptidase S1/S6, chymotrypsin/Hap; KEGG: hma:rrnAC0296 serine protease HtrA.
  
 
 0.834
AEN05347.1
PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: hwa:HQ2681A transmembrane oligosaccharyl transferase.
  
 
 0.824
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.809
AEN04598.1
PFAM: Exosortase EpsH-related; KEGG: hwa:HQ1604A hypothetical protein.
  
   
 0.806
atpE
V-type proton ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.805
AEN05627.1
PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: hma:rrnAC2133 mRNA 3'-end processing factor.
   
 
  0.785
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
     0.782
atpF
V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 
  0.781
AEN06344.1
Peptidase M50; KEGG: hwa:HQ1095A metalloprotease/metallo peptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF.
 
  
 0.778
AEN05759.1
KEGG: adn:Alide_4134 hypothetical protein.
  
  0.775
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.