Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06598.1KEGG: nph:NP4176A phosphatidylserine decarboxylase; PFAM: Phosphatidylserine decarboxylase-related. (203 aa)    
Predicted Functional Partners:
AEN06531.1
PFAM: Methyltransferase type 11; KEGG: hla:Hlac_1585 methyltransferase type 11.
  
  
  0.923
AEN06599.1
KEGG: hla:Hlac_2519 replication factor C small subunit 2; PFAM: Replication factor C; ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core.
       0.878
AEN04806.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hvo:HVO_1143 CDP-diacylglycerol-serine O phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.805
AEN04598.1
PFAM: Exosortase EpsH-related; KEGG: hwa:HQ1604A hypothetical protein.
     
 0.725
AEN06597.1
PFAM: Protein of unknown function DUF1508; KEGG: hla:Hlac_3547 protein of unknown function DUF1508.
       0.608
AEN06600.1
KEGG: hut:Huta_2747 hypothetical protein.
       0.510
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
      
 0.498
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
      
 0.494
AEN05177.1
HAMAP: UPF0173 metal-dependent hydrolase; KEGG: hma:rrnAC0300 hypothetical protein; Belongs to the UPF0173 family.
 
 
   0.481
AEN06886.1
Band 7 protein; KEGG: hbo:Hbor_24160 SPFH domain, band 7 family protein; PFAM: Band 7 protein; SMART: Band 7 protein.
   
   0.476
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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