Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (309 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.802
AEN06602.1
PFAM: Protein of unknown function DUF460; KEGG: hbo:Hbor_29620 hypothetical protein.
       0.699
AEN06599.1
KEGG: hla:Hlac_2519 replication factor C small subunit 2; PFAM: Replication factor C; ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core.
       0.624
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
   
 0.599
rtcB
Protein of unknown function UPF0027; PFAM: Uncharacterised protein family UPF0027; KEGG: hvo:HVO_2712 RNA terminal phosphate cyclase operon orfB-like protein; Belongs to the RtcB family.
 
   
 0.599
endA
tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
  
 0.579
AEN05627.1
PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: hma:rrnAC2133 mRNA 3'-end processing factor.
     
 0.558
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.542
cysS
TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; KEGG: hvo:HVO_1125 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR.
   
  
 0.539
rnj
Putative hydrolase; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
      
 0.538
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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