Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
AEN06602.1PFAM: Protein of unknown function DUF460; KEGG: hbo:Hbor_29620 hypothetical protein. (662 aa)    
Predicted Functional Partners:
AEN07282.1
PFAM: Uncharacterised conserved protein UCP022079; KEGG: hla:Hlac_1933 hypothetical protein.
  
     0.705
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.699
AEN04568.1
KEGG: hla:Hlac_0795 hypothetical protein.
  
     0.697
tfe
Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...]
  
     0.690
AEN06410.1
PRC-barrel domain protein; PFAM: PRC-barrel; KEGG: hvo:HVO_1964 PRC-barrel domain-containing protein.
  
     0.686
AEN04514.1
Protein of unknown function DUF555; PFAM: Uncharacterised protein family UPF0212; KEGG: htu:Htur_2443 protein of unknown function DUF555.
  
     0.682
AEN06573.1
PFAM: Protein of unknown function DUF2072, Zinc-ribbon; KEGG: hvo:HVO_3012 hypothetical protein.
  
     0.677
AEN06574.1
PFAM: Uncharacterised conserved protein UCP004977; KEGG: nmg:Nmag_1928 hypothetical protein.
  
     0.675
AEN05223.1
UPF0212 protein; KEGG: hbo:Hbor_16680 hypothetical protein; HAMAP: Uncharacterised protein family UPF0212; PFAM: Uncharacterised protein family UPF0212; Belongs to the UPF0212 family.
  
     0.661
AEN05417.1
Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain protein; PFAM: Protein of unknown function DUF293, archaea; KEGG: hbo:Hbor_16490 transcriptional regulator, contains C-terminal cbs domains.
  
     0.661
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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