Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
polCDNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1431 aa)    
Predicted Functional Partners:
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
   
 0.989
AEN06612.1
PFAM: Protein of unknown function DUF296; KEGG: hbo:Hbor_01610 DNA-binding protein with pd1-like DNA-binding motif.
       0.936
AEN06576.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
 
   
 0.852
AEN05599.1
SMART: ATPase, AAA+ type, core; KEGG: nmg:Nmag_2694 ORC1/cdc6 family replication initiation protein.
 
   
 0.790
AEN06640.1
Cell division control protein 6-like protein; Involved in regulation of DNA replication.
 
   
 0.743
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.724
AEN05047.1
KEGG: hbo:Hbor_25200 hypothetical protein.
  
     0.718
AEN04737.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: hbo:Hbor_01460 single-stranded DNA-specific exonuclease.
 
   
 0.710
AEN07051.1
Transcriptional regulator, XRE family; KEGG: nph:NP5106A ATP-dependent DNA helicase (intein-containing); PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: DNA-dependent ATPase MCM; Hedgehog/intein hint, N-terminal; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; Belongs to the MCM family.
 
   
 0.702
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.700
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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