Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06643.1PFAM: Protein of unknown function DUF373; KEGG: hvo:HVO_0302 hypothetical protein. (374 aa)    
Predicted Functional Partners:
AEN06641.1
PFAM: Radical SAM; KEGG: nmg:Nmag_1383 radical SAM domain protein.
 
     0.892
AEN07255.1
KEGG: hla:Hlac_1971 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
 
     0.711
mptE
Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
     0.704
ribK
Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.672
AEN05690.1
PUA domain containing protein; KEGG: hbo:Hbor_06070 tRNA-archaeosine synthase; PFAM: Pseudouridine synthase/archaeosine transglycosylase; Queuine/other tRNA-ribosyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
  
   
 0.671
dtdA
D-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
     0.667
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.639
AEN04587.1
KEGG: hvo:HVO_1107 hypothetical protein; PFAM: Protein of unknown function DUF1119, archaea; SMART: Peptidase A22, presenilin signal peptide.
  
     0.624
AEN06577.1
TIGRFAM: Peptidase S26B, eukaryotic signal peptidase; KEGG: hvo:HVO_0002 signal peptidase I.
  
     0.622
AEN04628.1
KEGG: hla:Hlac_0452 hypothetical protein.
 
     0.613
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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