Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06667.1PFAM: MgtE integral membrane region; KEGG: hvo:HVO_0124 divalent cation transporter domain-containing protein. (193 aa)    
Predicted Functional Partners:
AEN06666.1
PFAM: MgtE integral membrane region; KEGG: hbo:Hbor_00980 cation transporter.
 
    
0.920
AEN06907.1
PhoU family protein; PFAM: PhoU; Regulator of K+ conductance, C-terminal; KEGG: hut:Huta_1522 TrkA-C domain protein.
 
     0.840
AEN06668.1
PFAM: Major facilitator superfamily MFS-1; KEGG: hmu:Hmuk_0319 major facilitator superfamily MFS_1.
       0.631
srp54
Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.480
AEN06669.1
KEGG: nmg:Nmag_3971 peptidase S9 prolyl oligopeptidase active site domain protein.
  
    0.457
AEN07039.1
CoA-binding domain protein; PFAM: CoA-binding; KEGG: hje:HacjB3_02265 acetyl-CoA synthetase.
       0.423
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (10%) [HD]