STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN06671.1PFAM: Proteasome, subunit alpha/beta; KEGG: hje:HacjB3_15195 20S proteasome A and B subunits. (173 aa)    
Predicted Functional Partners:
psmB
Proteasome endopeptidase complex, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
     
  0.988
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.970
psmA-2
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.933
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 0.728
AEN06328.1
SMART: ATPase, AAA+ type, core; TIGRFAM: 26S proteasome subunit P45; KEGG: hbo:Hbor_05530 proteasome-activating nucleotidase; PFAM: ATPase, AAA-type, core; Belongs to the AAA ATPase family.
  
 0.728
pfdA
Prefoldin subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
  
 0.718
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.716
rpl18a
PFAM: Ribosomal protein LX; KEGG: hmu:Hmuk_1231 ribosomal LX protein.
  
    0.685
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.677
AEN04927.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: hbo:Hbor_21950 proteasome rpn11 subunit jamm motif protein.
   
 0.578
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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