Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06694.1Transcriptional regulator, XRE family; HAMAP: HTH-type transcriptional regulatory protein; PFAM: Helix-turn-helix type 3; KEGG: hbo:Hbor_28330 transcriptional regulator, xre family; SMART: Helix-turn-helix type 3. (326 aa)    
Predicted Functional Partners:
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
 
     0.914
AEN05448.1
UPF0179 protein; KEGG: hvo:HVO_2851 hypothetical protein; HAMAP: UPF0179 protein; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
  
     0.736
AEN04628.1
KEGG: hla:Hlac_0452 hypothetical protein.
 
     0.715
AEN05910.1
TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: hma:rrnAC3263 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.706
AEN05690.1
PUA domain containing protein; KEGG: hbo:Hbor_06070 tRNA-archaeosine synthase; PFAM: Pseudouridine synthase/archaeosine transglycosylase; Queuine/other tRNA-ribosyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
  
     0.700
mptD
Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.697
AEN04927.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: hbo:Hbor_21950 proteasome rpn11 subunit jamm motif protein.
  
     0.695
AEN07060.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hbo:Hbor_28820 hypothetical protein.
 
     0.691
AEN06168.1
Hypothetical protein; Manually curated; KEGG: hut:Huta_0046 hypothetical protein.
  
     0.686
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.684
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.