Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEN06695.1PFAM: Glutaredoxin; KEGG: hbo:Hbor_28340 glutathione S-transferase. (85 aa)    
Predicted Functional Partners:
AEN05807.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.753
AEN06899.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.715
AEN06697.1
PFAM: Xanthine/uracil/vitamin C permease; KEGG: hbo:Hbor_28360 permease.
       0.622
AEN04567.1
PFAM: Glutaredoxin; KEGG: hbo:Hbor_22700 glutaredoxin-related protein.
 
 0.554
AEN06696.1
KEGG: hwa:HQ3226A hypothetical protein.
       0.526
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.490
AEN05500.1
KEGG: nmg:Nmag_0021 iron-sulfur cluster assembly accessory protein; TIGRFAM: FeS cluster insertion; PFAM: FeS cluster biogenesis.
  
  
 0.458
AEN04719.1
TIGRFAM: Cysteine desulfurase, SufS; KEGG: hbo:Hbor_34450 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; NIF system FeS cluster assembly, NifU, N-terminal.
  
 
 0.436
AEN04839.1
KEGG: hma:rrnAC0905 hypothetical protein.
  
     0.420
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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