Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06698.1PFAM: Phosphoribosyltransferase; KEGG: hbo:Hbor_28370 prpp-binding protein, adenine/guanine phosphoribosyltransferase. (238 aa)    
Predicted Functional Partners:
AEN06697.1
PFAM: Xanthine/uracil/vitamin C permease; KEGG: hbo:Hbor_28360 permease.
  
  
 0.890
pyrE-2
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.772
AEN04577.1
TIGRFAM: Adenylosuccinate lyase; KEGG: hbo:Hbor_22730 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.641
guaAB
GMP synthase (glutamine-hydrolyzing) subunit B; Catalyzes the synthesis of GMP from XMP.
  
 
 0.629
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.614
AEN06864.1
PFAM: Phosphoribosyltransferase; KEGG: hvo:HVO_0694 purine phosphoribosyltransferase.
 
 
 0.613
AEN06167.1
KEGG: hvo:HVO_1134 hypothetical protein.
  
     0.592
AEN05669.1
KEGG: hmu:Hmuk_1377 hypothetical protein.
 
  
 0.572
AEN04576.1
Phosphoribosylglycinamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, formylation region; TIGRFAM: Phosphoribosylglycinamide formyltransferase; KEGG: hla:Hlac_0925 phosphoribosylglycinamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme, formylation region; Formyl transferase, N-terminal.
  
 
 0.555
srp54
Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.551
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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