Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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carSUPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (180 aa)    
Predicted Functional Partners:
AEN04623.1
KEGG: hmu:Hmuk_3091 FAD dependent oxidoreductase; TIGRFAM: Geranylgeranyl reductase, plant/prokaryotic; PFAM: FAD dependent oxidoreductase.
  
  
 0.938
AEN04806.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hvo:HVO_1143 CDP-diacylglycerol-serine O phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.914
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
   
 0.787
pfdB
Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
     0.771
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
    0.769
AEN04586.1
KEGG: htu:Htur_0798 PUA domain containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
  
     0.721
rpl21e
KEGG: hbo:Hbor_12170 LSU ribosomal protein l21e; HAMAP: 50S ribosomal protein L21e; PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
     0.705
rps27e
KEGG: hvo:HVO_0700 30S ribosomal protein S27.eR; HAMAP: 30S ribosomal protein S27e; PFAM: Ribosomal protein S27e.
 
     0.691
AEN06694.1
Transcriptional regulator, XRE family; HAMAP: HTH-type transcriptional regulatory protein; PFAM: Helix-turn-helix type 3; KEGG: hbo:Hbor_28330 transcriptional regulator, xre family; SMART: Helix-turn-helix type 3.
  
     0.674
AEN05302.1
KEGG: hvo:HVO_1593 3-isopropylmalate dehydratase.
  
     0.667
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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