Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pfdBPrefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (129 aa)    
Predicted Functional Partners:
pfdA
Prefoldin subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 0.996
rpoP
DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
  
 0.907
AEN06702.1
KEGG: hbo:Hbor_25590 hypothetical protein.
       0.907
AEN06335.1
PFAM: DNA-binding TFAR19-related protein; KEGG: hbo:Hbor_04590 DNA-binding tfar19-related protein; Belongs to the PDCD5 family.
 
   0.843
rpl37ae
Ribosomal L37ae protein; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family.
 
  
 0.795
carS
UPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
 
     0.771
ef1b
Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
    0.766
rpl21e
KEGG: hbo:Hbor_12170 LSU ribosomal protein l21e; HAMAP: 50S ribosomal protein L21e; PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
  
 0.763
AEN04728.1
PFAM: Tetratricopeptide TPR-1; KEGG: hbo:Hbor_01120 tetratricopeptide hypothetical protein.
  
  0.754
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
    0.690
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.